College Football Week Four Preview:

Syracuse-Clemson, Florida-#4 Miami,
#9 Illinois-#19 IU Among National Highlights
(DG’s “This Week In CFB” YouTube Show = below)


By David Glenn
North Carolina Sports Network
(last updated Sept. 17, 2025)

The 2025 college football season continues Thursday through Saturday with a compelling Week Four schedule.

The most prominent games nationally this week (each previewed below) include a battle of undefeated and highly ranked Big Ten squads (#9 Illinois at #19 Indiana, 7:30 p.m., NBC), a Sunshine State showdown between two long-time rivals who haven’t played each other as often in recent decades (Florida at #4 Miami, 7:30 p.m., ABC) and an all-ACC matchup that includes two quarterbacks drawing big headlines for very different reasons (Syracuse at Clemson, noon, ESPN).

Meanwhile, in the Old North State, Charlotte is serving as host for ESPN’s exclusive Thursday night television window, Duke and NC State are revisiting their traditional rivalry, ECU is hosting undefeated BYU, the “Aggie-Eagle Classic” is back in Greensboro, and UNC is visiting UCF in yet another network TV game, among other interesting storylines.


Here are more details on our “Three To See” selections from this week’s national schedule:

National “Three To See,” Game One

Syracuse (2-1) at Clemson (1-2), Sat., noon (ESPN)

As with this week’s NC State-Duke game, this Syracuse-Clemson matchup is one where the records are definitely misleading.

The Orange are 2-1, but they got stomped by Tennessee, and they needed overtime to beat a mediocre UConn squad, leading second-year coach Fran Brown to demand some postgame wind sprints in the aftermath.

Clemson is 1-2, but those two losses are to an LSU team that’s now 3-0 and #3 in the national rankings and a Georgia Tech squad that’s now 3-0 and #18 in the national rankings.

Meanwhile, despite having a bunch of NFL-caliber talent on hand, this definitely does not look like one of coach Dabo Swinney’s vintage Clemson teams, on either side of the ball.

At the same time, while the Tigers have absolutely no margin for error at this point, they expect to get star players such as left tackle Tristan Leigh, wide receiver Antonio Williams and safety Khalil Barnes back from injuries at some point soon, so at this stage it may be wise to advise against counting them out in the race for one of those two spots in the ACC championship game.

The greatest strength on Syracuse’s team so far this season has been its new starting quarterback, Steve Angeli, a Notre Dame transfer who is leading the nation with 357 passing yards per game. However, Angeli is not a runner, and he’s not very mobile, so you can expect that Clemson’s defense — starting with potential first-round NFL picks in defensive linemen Peter Woods and TJ Parker — will be all over him from the opening snap.

The Orange could not run the ball against either Tennessee or UConn. If that trend continues, it will be virtually impossible for their line to keep the pressure off Angeli, who’s already been sacked eight times this season.

When Clemson (a 17-point favorite) has the ball, the Tigers will be going against a more vulnerable defense than they saw in their losses to LSU and Georgia Tech, when they managed only a combined 31 points. Even in their win over Troy, the Tigers scored only 27 points.

This is Clemson’s third year under high-profile offensive coordinator Garrett Riley, brother of Southern Cal head coach Lincoln Riley. Garrett joined the Tigers right after directing TCU’s prolific offense during the Horned Frogs 13-2 season that ended in the 2022 national championship game.

It would help a lot to get Leigh back at left tackle and Williams back at wide receiver, but in the meantime senior Cade Klubnik needs to be better at quarterback, converted receiver Adam Randall and others have to be better at tailback, someone needs to step forward as a dangerous tight end, and someone besides Bryant Wesco Jr. needs to step up at wide receiver.


National “Three To See,” Game Two

Florida (1-2) at #4 Miami (3-0), Sat., 7:30 p.m. (ABC)

There is an absolutely wild set of circumstances surrounding this game.

The Florida-Miami clash was played every single year for decades, but not nearly as often since the mid-1980s, right around the time that Miami went from a no-name program to one that won four national championships in a nine-year period — first under Howard Schnellenberger in 1983, then under Jimmy Johnson in 1987, then two more under Dennis Erickson.

Since 1987 — that’s almost 40 years ago now — the Gators and Hurricanes have played only eight times. Miami has won six of those eight, including last year in Gainesville, which was the first time Florida coach Billy Napier and Canes coach Mario Cristobal went head-to-head in this rivalry.

Although Florida is a three-time national championship program — once under Steve Spurrier, twice under Urban Meyer — the Gators haven’t been great very often since Meyer stepped away 15 years ago. Similarly, although Miami is a five-time national championship program — most recently under Larry Coker in 2001 — the Canes haven’t been great very often since they joined the ACC in 2004.

The expectations are high for every coach, almost every year, at these two schools, and both Napier and Cristobal are in their fourth season.

Both coaches have had mediocre results so far, with one exception — Cristobal broke through last year, thanks largely to sensational quarterback Cam Ward (now starting for the NFL’s Tennessee Titans), who led the Canes to a 10-3 campaign. Napier, on the other hand, hasn’t broken through with a big season yet, and many consider him on the Hot Seat after the Gators’ disappointing 1-2 start this year.

Beyond the Hot Seat conversation that surrounds Napier, there’s another circus-like sideshow around Florida quarterback DJ Lagway, who threw five interceptions — including a back-breaking pick-six — in last week’s 20-10 loss at #3 LSU. The Gators also struggled offensively in their 18-16 home loss to South Florida, a team that Miami just mauled by a 49-12 margin.

Lagway, the 2023 National High School Player of the Year, went 6-1 as a starter last year for Florida as a true freshman, but he’s playing at almost 250 pounds now, isn’t much of a running threat, and has made a bunch of really bad decisions under pressure. Meanwhile, there’s talk in Gainesville that many UF players aren’t fully behind Lagway, who got a huge revenue-sharing deal in the offseason that may be impacting the team’s locker-room chemistry.

Miami, meanwhile, has looked like a much more well-rounded team than it was even during last year’s 10-3 campaign, when Ward often had to save the Canes in high-scoring shootouts.

This UM team already has defeated two ranked opponents, Notre Dame and South Florida, while giving up only 13 points per game during its 3-0 start.

Georgia transfer Carson Beck has been the opposite of Lagway for the Canes — accurate thrower, reliable decision-maker, strong leader, productive passer.

Florida (a seven-point underdog) actually does have a very stout defense, so there will be plenty of NFL-caliber talent on the field for both sides when the Canes have the ball, but the mood will be much different when the Gators are in possession and the Napier/Lagway combo is back under the heat lamp.

National “Three To See,” Game Three

#9 Illinois (3-0) at #19 Indiana (3-0), Sat., 7:30 p.m. (NBC)

This game is included partly because both teams are undefeated and ranked in the Top 25 — duh — but also partly because they’re great examples of middling programs that have become relevant on the national scene in back-to-back seasons after very long slumbers.

In North Carolina, college football fans often talk about how NC State and UNC — the state’s two large, public universities competing in a Power Four league — have not captured a conference title on the gridiron since 1979 and 1980, respectively. That’s a long time ago. If you’re 50 years old or younger, you probably don’t even remember those Wolfpack and Tar Heel title teams.

Well, Illinois has only one Big Ten football title since 1990, and Indiana — much better known for basketball (sound familiar?) — hasn’t won a Big Ten football championship since 1967. In addition, the Illini have had only four Top 25 finishes in football since 1990, and the Hoosiers have had only two Top 25 finishes since 1988.

Some of those numbers are even worse than the comparable numbers for UNC football and NC State football.

One aspect of the developing Illinois and Indiana stories that is much harder to duplicate has to do with money.

Over the past two decades, thanks largely to coast-to-coast conference expansion and football TV revenue, the Big Ten has become the wealthiest conference in America. Last year, for example, long-standing Big Ten members each received payments of more than $63 million from their league office. That number in the ACC was about $45 million per school. That’s an enormous gap.

Whereas the ACC was the wealthiest conference in America for most of the 1980s, 1990s and even early 2000s, those days are long gone, largely because the league’s football TV product doesn’t attract nearly as many eyeballs, overall, as the football TV products in the Big Ten and the SEC.

The other aspect of the Illinois and Indiana stories that’s very important to learn from is finding the right head coach.

Even as Illinois and Indiana got wealthier, they didn’t really take off as football programs until they hired Bret Bielema and Curt Cignetti, respectively. These were guys with really impressive, proven track records.

Bielema, an Illinois native, had great success over a seven-year period as the head coach at Wisconsin of the Big Ten. Cignetti had nothing but success at all three of his previous head coaching stops, include back-to-back Top 25 seasons at Elon in the FCS ranks, then three straight trips to the FCS playoff semifinals while at James Madison, which he then helped successfully transition to the FBS as a member of the Sun Belt Conference.

If you watch this year’s Illinois-Indiana game on NBC on Saturday night, keep these backdrop elements in mind. If it can happen there, it can happen here, too.

NOTE: For the in-state edition of our Week Four college football preview, including analysis on the highest-profile games, plus schedules and TV/streaming options for all 32 teams (FBS, FCS, Division Two, Division Three) in the Bold North State, please click HERE.